More Vyper guides
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Overview
Vyper is a assassin in Deadlock: slither in and assassinate enemies. Over the last two weeks it is B tier: 49.0% win rate in 107,154 games, picked in 18.9% of matches.
Build cheat sheet
Pick the build that fits what you want to do this game.
- Vyper: most played buildBalancedRecommendedThe items Vyper players buy most in each phase of the game over the last two weeks (107,154 games measured), with how many buy them and how they do. Skill points in the most played order (6,328 games, 52.2% win rate).
- Vyper: “Rey's Compy Wizard Lizard (GUIDED!)” (in-game build)UtilityAdvancedThe most favorited Vyper build published in the game this patch: saved 29,140 times, last updated on 2026-09-30. Find it in-game in the Hero Builds browser by its ID: 196233. Its own categories are kept as notes on each item.
Builds
Vyper: most played build
When to use it
The items Vyper players buy most in each phase of the game over the last two weeks (107,154 games measured), with how many buy them and how they do. Skill points in the most played order (6,328 games, 52.2% win rate).
Laning phase
Mid game
- 1Burst FireBought by 58.7% of players in this phase · 49.5% win rate
- 2Split ShotBought by 46.4% of players in this phase · 47.4% win rate
- 3Quicksilver ReloadBought by 40.4% of players in this phase · 48.2% win rate
- 4Tesla BulletsBought by 33.5% of players in this phase · 48.7% win rate
- 5Bullet LifestealBought by 27.6% of players in this phase · 47.4% win rate
- 6Extra StaminaBought by 26.3% of players in this phase · 46.4% win rate
Late game
Skill order
Max order:3›2›1
Vyper: “Rey's Compy Wizard Lizard (GUIDED!)” (in-game build)
When to use it
The most favorited Vyper build published in the game this patch: saved 29,140 times, last updated on 2026-09-30. Find it in-game in the Hero Builds browser by its ID: 196233. Its own categories are kept as notes on each item.
This build is published in the game: copy its ID and search it in the Hero Builds browser to load it.
196233Laning phase
Mid game
- 1Point Blankpick ONE (in order of my prefrence)
- 2Toxic Bulletspick ONE (in order of my prefrence)
- 3Blood Tributepick ONE (in order of my prefrence)
- 4Bullet Resist ShredderOther Strong Items
- 5Escalating ResilienceOther Strong Items
- 6Swift StrikerOther Strong Items
- 7Split ShotOther Strong Items
- 8Hunter's AuraOther Strong Items
- 9SilencerOther Strong Items
- 10InhibitorOther Strong Items
- 11SpellslingerOther Strong Items
- 12Glass CannonOther Strong Items
Late game
Skill order
Max order:2›3›1
Abilities
1Screwjab Dagger10sThrow a dagger, dealing spirit damage and applying slow. Every subsequent dagger against the same target stacks in spirit damage and slow.- Damage
- 50
- Move Speed
- -28%
- Damage per Stack
- 25
- Move Speed per Stack
- -12%
- Stack Duration
- 10s
- Charges
- 2
2Lethal Venom28sInject a target with lethal venom. After a delay the venom triggers, dealing Spirit Damage. The damage is increased by the target's missing health. Lethal Venom will ignore Petrify's damage block.- Minimum Venom Damage
- 20
- Max Venom Damage
- 140
- Health for Max Damage
- 30%
- Venom Buildup Duration
- 3s
3SlitherYou have increased Slide Distance, can Slide up hills, and can turn faster while Sliding.- Slide Distance
- +15%
4Petrifying BolaUltimate115sThrow an explosive bola. On exploding, the bola Slows and Damages all enemies in the area. Direct hits deal Additional Damage and Petrify instead. Petrified units block all damage, but cannot take actions.- Damage
- 50
- Petrify Damage
- 180
- Move Speed
- -40%
- Slow Duration
- 1.5s
Most played skill order
The most played order in the last 6328 professional matches with this hero. Highlighted levels are the points spent on talents.
Max order:3›2›1
Strategy
11 · Screwjab Dagger
Throw a dagger, dealing spirit damage and applying slow. Every subsequent dagger against the same target stacks in spirit damage and slow.
- T1: +1 Charges
- T2: On Hit: -8% Bullet Resist and -6% Bullet Resist per Stack
- T3: +2 Max Stacks -2s Charge Delay On Hit: Refund 55% Charge Cooldown
22 · Lethal Venom
Inject a target with lethal venom. After a delay the venom triggers, dealing Spirit Damage. The damage is increased by the target's missing health. Lethal Venom will ignore Petrify's damage block.
- T1: +31.5 Max Venom Damage
- T2: -40% Incoming Healing and -12s Cooldown
- T3: Bullets also build up Lethal Venom
33 · Slither
You have increased Slide Distance, can Slide up hills, and can turn faster while Sliding.
- T1: +20% Slide Distance
- T2: +2 Stamina
- T3: On Slide: Gain 180 barrier for 4s
44 · Petrifying Bola
Throw an explosive bola. On exploding, the bola Slows and Damages all enemies in the area. Direct hits deal Additional Damage and Petrify instead. Petrified units block all damage, but cannot take actions.
- T1: +49.5 Petrify Damage
- T2: -20s Cooldown
- T3: +1.0s Petrify Duration. Petrifies all enemies in the area.
5Skill order
The most played skill order (6,328 games, 52.2% win rate) goes 3 · 3 · 2 · 2 · 1 · 3 · 4 · 3 · 2 · 2 · 4 · 4 · 4 · 1 · 1. The one that wins most among the common ones (2,114 games) reaches 66.3%: 3 · 3 · 1 · 2 · 2 · 3 · 4 · 3 · 2 · 2 · 4 · 4 · 4 · 1 · 1 · 1.
- Each ability takes four steps: the unlock, then three upgrades that cost 1, 2 and 5 ability points (T1, T2, T3).
Tips
- Unlock order most players use: Slither (3) → Lethal Venom (2) → Screwjab Dagger (1) → Petrifying Bola (4).
- Upgrade Slither first, then Lethal Venom; put points in the ultimate when you can.
Matchups
Strong against
- Mirage55.3%win rate in the matchup
Vyper wins 55.3% of the 8,394 games measured against Mirage in the last two weeks.
8.4K matches
- Viscous54.1%win rate in the matchup
Vyper wins 54.1% of the 10,402 games measured against Viscous in the last two weeks.
10.4K matches
- Sinclair54.1%win rate in the matchup
Vyper wins 54.1% of the 9,544 games measured against Sinclair in the last two weeks.
9.5K matches
- The Doorman54.0%win rate in the matchup
Vyper wins 54.0% of the 10,042 games measured against The Doorman in the last two weeks.
10K matches
- Shiv53.5%win rate in the matchup
Vyper wins 53.5% of the 21,256 games measured against Shiv in the last two weeks.
21.3K matches
Weak against
- Graves41.6%win rate in the matchup
Vyper only wins 41.6% of the 20,543 games measured against Graves in the last two weeks.
20.5K matches
- Victor42.9%win rate in the matchup
Vyper only wins 42.9% of the 17,990 games measured against Victor in the last two weeks.
18K matches
- Paige43.1%win rate in the matchup
Vyper only wins 43.1% of the 19,612 games measured against Paige in the last two weeks.
19.6K matches
- Seven44.5%win rate in the matchup
Vyper only wins 44.5% of the 18,422 games measured against Seven in the last two weeks.
18.4K matches
- Mo & Krill45.2%win rate in the matchup
Vyper only wins 45.2% of the 14,911 games measured against Mo & Krill in the last two weeks.
14.9K matches
Works well with
- Paige56.4%win rate in the matchup
Vyper and Paige on the same team win 56.4% of 4,211 games measured in the last two weeks.
4.2K matches
- Graves55.4%win rate in the matchup
Vyper and Graves on the same team win 55.4% of 3,784 games measured in the last two weeks.
3.8K matches
- Seven55.0%win rate in the matchup
Vyper and Seven on the same team win 55.0% of 2,372 games measured in the last two weeks.
2.4K matches
- Victor54.8%win rate in the matchup
Vyper and Victor on the same team win 54.8% of 2,330 games measured in the last two weeks.
2.3K matches
- Kelvin54.4%win rate in the matchup
Vyper and Kelvin on the same team win 54.4% of 1,933 games measured in the last two weeks.
1.9K matches
Changelog
- Guide created for patch 2026-09-16.
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