Vyper · Assassin
Vyper guide
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This guide is assembled by the site from match data and the game's own information — nobody wrote it by hand. Official and community guides appear alongside it when they exist.
Overview
Vyper is a assassin in Deadlock: slither in and assassinate enemies. Over the last two weeks it is B tier: 49.0% win rate in 107,154 games, picked in 18.9% of matches. With a powerful weapon (and deadly venom to match), Vyper can slither into the back of teams and assassinate high-priority targets in a storm of bullets.
Strengths
- One of the strongest guns in the game: 94 base weapon DPS, #2 of 38 heroes.
- A strong pusher: 11,655 objective damage per game on average (median 6,198).
- Where it wins most: Ascendant games (55.7%).
- Wins the lane against Mirage: 56.0% of 2,886 games with both in the same lane.
- Valve rates Vyper as easy to pick up: a good first hero.
Weaknesses
- Short-range gun: damage falls off from 15 m, so it has to fight up close.
- Where it wins least: Initiate games (47.2%).
- Struggles against Graves in lane: only 42.3% of 6,858 games.
Build cheat sheet
Pick the build that fits what you want to do this game.
- Vyper: most played buildBalancedRecommendedThe items Vyper players buy most in each phase of the game over the last two weeks (107,154 games measured), with how many buy them and how they do. Skill points in the most played order (6,328 games, 52.2% win rate).
- Vyper: “Rey's Compy Wizard Lizard (GUIDED!)” (in-game build)UtilityAdvancedThe most favorited Vyper build published in the game this patch: saved 29,140 times, last updated on 2026-09-30. Find it in-game in the Hero Builds browser by its ID: 196233. Its own categories are kept as notes on each item.
- Vyper: highest win rate itemsOffensiveSituationalItems with the highest win rate when bought on Vyper, among those bought in a meaningful share of games, placed by when they are bought on average. Win rate on items bought late is inflated by games that were already going well: read it as “what winning Vypers end up buying”.
- Vyper: vitality buildDefensiveSituationalThe vitality items Vyper players buy most, for games where you get focused or need to survive fights longer. Cheapest first.
Builds
Vyper: most played build
When to use it
The items Vyper players buy most in each phase of the game over the last two weeks (107,154 games measured), with how many buy them and how they do. Skill points in the most played order (6,328 games, 52.2% win rate).
Laning phase
Mid game
- 1Burst FireBought by 58.7% of players in this phase · 49.5% win rate
- 2Split ShotBought by 46.4% of players in this phase · 47.4% win rate
- 3Quicksilver ReloadBought by 40.4% of players in this phase · 48.2% win rate
- 4Tesla BulletsBought by 33.5% of players in this phase · 48.7% win rate
- 5Bullet LifestealBought by 27.6% of players in this phase · 47.4% win rate
- 6Extra StaminaBought by 26.3% of players in this phase · 46.4% win rate
Late game
Skill order
Max order:3›2›1
| Ability | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
 1 | · | · | · | · | 1 | · | · | · | · | · | · | · | · | 1 | 1 |
 2 | · | · | 2 | 2 | · | · | · | · | 2 | 2 | · | · | · | · | · |
 3 | 3 | 3 | · | · | · | 3 | · | 3 | · | · | · | · | · | · | · |
 4 | · | · | · | · | · | · | 4 | · | · | · | 4 | 4 | 4 | · | · |
Vyper: “Rey's Compy Wizard Lizard (GUIDED!)” (in-game build)
When to use it
The most favorited Vyper build published in the game this patch: saved 29,140 times, last updated on 2026-09-30. Find it in-game in the Hero Builds browser by its ID: 196233. Its own categories are kept as notes on each item.
This build is published in the game: copy its ID and search it in the Hero Builds browser to load it.
196233Laning phase
Mid game
- 1Point Blankpick ONE (in order of my prefrence)
- 2Toxic Bulletspick ONE (in order of my prefrence)
- 3Blood Tributepick ONE (in order of my prefrence)
- 4Bullet Resist ShredderOther Strong Items
- 5Escalating ResilienceOther Strong Items
- 6Swift StrikerOther Strong Items
- 7Split ShotOther Strong Items
- 8Hunter's AuraOther Strong Items
- 9SilencerOther Strong Items
- 10InhibitorOther Strong Items
- 11SpellslingerOther Strong Items
- 12Glass CannonOther Strong Items
Late game
Skill order
Max order:2›3›1
| Ability | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 1 | · | · | · | · | · | · | · | · | · | · | · | · | 1 | 1 | 1 |
| 2 | · | 2 | · | · | 2 | · | · | · | 2 | 2 | · | · | · | · | · | · |
| 3 | · | · | 3 | · | · | · | · | 3 | · | · | 3 | · | 3 | · | · | · |
| 4 | · | · | · | 4 | · | 4 | 4 | · | · | · | · | 4 | · | · | · | · |
Vyper: highest win rate items
When to use it
Items with the highest win rate when bought on Vyper, among those bought in a meaningful share of games, placed by when they are bought on average. Win rate on items bought late is inflated by games that were already going well: read it as “what winning Vypers end up buying”.
Late game
Skill order
Max order:3›2›1
| Ability | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | · | · | 1 | · | · | · | · | · | · | · | · | · | · | 1 | 1 | 1 |
| 2 | · | · | · | 2 | 2 | · | · | · | 2 | 2 | · | · | · | · | · | · |
| 3 | 3 | 3 | · | · | · | 3 | · | 3 | · | · | · | · | · | · | · | · |
| 4 | · | · | · | · | · | · | 4 | · | · | · | 4 | 4 | 4 | · | · | · |
Vyper: vitality build
When to use it
The vitality items Vyper players buy most, for games where you get focused or need to survive fights longer. Cheapest first.
Laning phase
Mid game
- 1Stamina MasteryBought by 31.2% of players in this phase · 46.5% win rate
- 2Spirit ResilienceBought by 18.5% of players in this phase · 47.2% win rate
- 3FortitudeBought by 12.9% of players in this phase · 46.3% win rate
- 4Dispel MagicBought by 9.7% of players in this phase · 48.0% win rate
Late game
Skill order
Max order:3›2›1
| Ability | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | · | · | · | · | 1 | · | · | · | · | · | · | · | · | 1 | 1 |
| 2 | · | · | 2 | 2 | · | · | · | · | 2 | 2 | · | · | · | · | · |
| 3 | 3 | 3 | · | · | · | 3 | · | 3 | · | · | · | · | · | · | · |
| 4 | · | · | · | · | · | · | 4 | · | · | · | 4 | 4 | 4 | · | · |
Abilities
- 1Screwjab Dagger10sThrow a dagger, dealing spirit damage and applying slow. Every subsequent dagger against the same target stacks in spirit damage and slow.
- Damage
- 50
- Move Speed
- -28%
- Damage per Stack
- 25
- Move Speed per Stack
- -12%
- Stack Duration
- 10s
- Charges
- 2
- 2Lethal Venom28sInject a target with lethal venom. After a delay the venom triggers, dealing Spirit Damage. The damage is increased by the target's missing health. Lethal Venom will ignore Petrify's damage block.
- Minimum Venom Damage
- 20
- Max Venom Damage
- 140
- Health for Max Damage
- 30%
- Venom Buildup Duration
- 3s
- 3SlitherYou have increased Slide Distance, can Slide up hills, and can turn faster while Sliding.
- Slide Distance
- +15%
- 4Petrifying BolaUltimate115sThrow an explosive bola. On exploding, the bola Slows and Damages all enemies in the area. Direct hits deal Additional Damage and Petrify instead. Petrified units block all damage, but cannot take actions.
- Damage
- 50
- Petrify Damage
- 180
- Move Speed
- -40%
- Slow Duration
- 1.5s
Most played skill order
The most played order in the last 6328 professional matches with this hero. Highlighted levels are the points spent on talents.
Max order:3›2›1
| Ability | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | · | · | · | · | 1 | · | · | · | · | · | · | · | · | 1 | 1 |
| 2 | · | · | 2 | 2 | · | · | · | · | 2 | 2 | · | · | · | · | · |
| 3 | 3 | 3 | · | · | · | 3 | · | 3 | · | · | · | · | · | · | · |
| 4 | · | · | · | · | · | · | 4 | · | · | · | 4 | 4 | 4 | · | · |
Strategy
1Abilities
What each of Vyper's abilities does, as the game describes it:
- 1 · Screwjab Dagger — 10s cooldown: Throw a dagger, dealing spirit damage and applying slow. Every subsequent dagger against the same target stacks in spirit damage and slow.
- 2 · Lethal Venom — 28s cooldown: Inject a target with lethal venom. After a delay the venom triggers, dealing Spirit Damage. The damage is increased by the target's missing health. Lethal Venom will ignore Petrify's damage block.
- 3 · Slither: You have increased Slide Distance, can Slide up hills, and can turn faster while Sliding.
- 4 · Petrifying Bola (ultimate) — 115s cooldown: Throw an explosive bola. On exploding, the bola Slows and Damages all enemies in the area. Direct hits deal Additional Damage and Petrify instead. Petrified units block all damage, but cannot take actions.
2Skill order
The most played skill order (6,328 games, 52.2% win rate) goes 3 · 3 · 2 · 2 · 1 · 3 · 4 · 3 · 2 · 2 · 4 · 4 · 4 · 1 · 1. The one that wins most among the common ones (2,114 games) reaches 66.3%: 3 · 3 · 1 · 2 · 2 · 3 · 4 · 3 · 2 · 2 · 4 · 4 · 4 · 1 · 1 · 1.
3Items by phase
What Vyper players buy most in the laning phase, mid game and late game:
- Close Quarters — 73.3% buy it · 47.6% win rate
- Extra Spirit — 56.0% buy it · 47.4% win rate
- Rapid Rounds — 48.1% buy it · 46.7% win rate
- Burst Fire — 58.7% buy it · 49.5% win rate
- Split Shot — 46.4% buy it · 47.4% win rate
- Quicksilver Reload — 40.4% buy it · 48.2% win rate
- Mercurial Magnum — 60.8% buy it · 49.3% win rate
- Ricochet — 35.0% buy it · 53.6% win rate
- Stamina Mastery — 31.2% buy it · 46.5% win rate
4A typical game
An average Vyper game over the last two weeks: 8.2 kills, 7.8 deaths and 10.8 assists, 34,633 hero damage, 11,655 objective damage and 44,169 souls.
5Win rate by rank
By the average badge of the game:
- Initiate: 47.2% (2,380 games)
- Seeker: 48.8% (4,387 games)
- Acolyte: 48.9% (3,776 games)
- Sentinel: 52.8% (3,169 games)
- Mystic: 53.3% (2,901 games)
- Ritualist: 50.7% (2,908 games)
- Emissary: 52.6% (3,098 games)
- Oracle: 53.7% (3,876 games)
- Phantom: 51.8% (3,819 games)
- Ascendant: 55.7% (1,672 games)
- Eternus: 52.7% (461 games)
Tips
- Unlock order most players use: Slither (3) → Lethal Venom (2) → Screwjab Dagger (1) → Petrifying Bola (4).
- Upgrade Slither first, then Lethal Venom; put points in the ultimate when you can.
- First buys: Close Quarters, Extra Spirit and Rapid Rounds.
- Your gun hits hardest within 15 m; past 33 m it deals minimum damage.
- Last-hit troopers and shoot the soul orbs they drop: souls are your gold and your level.
- Deny the enemy's orbs when you can: every denied orb is souls they don't get.
Matchups
Strong against
- Mirage55.3%win rate in the matchup
Vyper wins 55.3% of the 8,394 games measured against Mirage in the last two weeks.
8.4K matches
- Viscous54.1%win rate in the matchup
Vyper wins 54.1% of the 10,402 games measured against Viscous in the last two weeks.
10.4K matches
- Sinclair54.1%win rate in the matchup
Vyper wins 54.1% of the 9,544 games measured against Sinclair in the last two weeks.
9.5K matches
- The Doorman54.0%win rate in the matchup
Vyper wins 54.0% of the 10,042 games measured against The Doorman in the last two weeks.
10K matches
- Shiv53.5%win rate in the matchup
Vyper wins 53.5% of the 21,256 games measured against Shiv in the last two weeks.
21.3K matches
Weak against
- Graves41.6%win rate in the matchup
Vyper only wins 41.6% of the 20,543 games measured against Graves in the last two weeks.
20.5K matches
- Victor42.9%win rate in the matchup
Vyper only wins 42.9% of the 17,990 games measured against Victor in the last two weeks.
18K matches
- Paige43.1%win rate in the matchup
Vyper only wins 43.1% of the 19,612 games measured against Paige in the last two weeks.
19.6K matches
- Seven44.5%win rate in the matchup
Vyper only wins 44.5% of the 18,422 games measured against Seven in the last two weeks.
18.4K matches
- Mo & Krill45.2%win rate in the matchup
Vyper only wins 45.2% of the 14,911 games measured against Mo & Krill in the last two weeks.
14.9K matches
Works well with
- Paige56.4%win rate in the matchup
Vyper and Paige on the same team win 56.4% of 4,211 games measured in the last two weeks.
4.2K matches
- Graves55.4%win rate in the matchup
Vyper and Graves on the same team win 55.4% of 3,784 games measured in the last two weeks.
3.8K matches
- Seven55.0%win rate in the matchup
Vyper and Seven on the same team win 55.0% of 2,372 games measured in the last two weeks.
2.4K matches
- Victor54.8%win rate in the matchup
Vyper and Victor on the same team win 54.8% of 2,330 games measured in the last two weeks.
2.3K matches
- Kelvin54.4%win rate in the matchup
Vyper and Kelvin on the same team win 54.4% of 1,933 games measured in the last two weeks.
1.9K matches
Changelog
- Guide created for patch 2026-09-16.
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