More Vyper guides
This guide is assembled by the site from match data and the game's own information — nobody wrote it by hand. Official and community guides appear alongside it when they exist.
Overview
Vyper is a assassin in Deadlock: slither in and assassinate enemies. Over the last two weeks it is B tier: 48.9% win rate in 108,706 games, picked in 19.0% of matches. In short: slither in and assassinate enemies.
Strengths
- One of the strongest guns in the game: 94 base weapon DPS, #2 of 38 heroes.
- A strong pusher: 11,636 objective damage per game on average (median 6,203).
- Where it wins most: Ascendant games (56.3%).
Weaknesses
- Where it wins least: Initiate games (46.4%).
Build cheat sheet
Pick the build that fits what you want to do this game.
Builds
Vyper: most played build
When to use it
The items Vyper players buy most in each phase of the game over the last two weeks (108,706 games measured), with how many buy them and how they do. Skill points in the most played order (6,239 games, 51.9% win rate).
Laning phase
Mid game
- 1Burst FireBought by 58.7% of players in this phase · 49.5% win rate
- 2Split ShotBought by 46.4% of players in this phase · 47.4% win rate
- 3Quicksilver ReloadBought by 40.4% of players in this phase · 48.2% win rate
- 4Tesla BulletsBought by 33.5% of players in this phase · 48.7% win rate
- 5Bullet LifestealBought by 27.6% of players in this phase · 47.4% win rate
- 6Extra StaminaBought by 26.3% of players in this phase · 46.4% win rate
Late game
Skill order
Max order:3›2›1
Abilities
1Screwjab Dagger10sThrow a dagger, dealing spirit damage and applying slow. Every subsequent dagger against the same target stacks in spirit damage and slow.- Damage
- 50
- Move Speed
- -28%
- Damage per Stack
- 25
- Move Speed per Stack
- -12%
- Stack Duration
- 10s
- Charges
- 2
2Lethal Venom28sInject a target with lethal venom. After a delay the venom triggers, dealing Spirit Damage. The damage is increased by the target's missing health. Lethal Venom will ignore Petrify's damage block.- Minimum Venom Damage
- 20
- Max Venom Damage
- 140
- Health for Max Damage
- 30%
- Venom Buildup Duration
- 3s
3SlitherYou have increased Slide Distance, can Slide up hills, and can turn faster while Sliding.- Slide Distance
- +15%
4Petrifying BolaUltimate115sThrow an explosive bola. On exploding, the bola Slows and Damages all enemies in the area. Direct hits deal Additional Damage and Petrify instead. Petrified units block all damage, but cannot take actions.- Damage
- 50
- Petrify Damage
- 180
- Move Speed
- -40%
- Slow Duration
- 1.5s
Most played skill order
The most played order in the last 6239 professional matches with this hero. Highlighted levels are the points spent on talents.
Max order:3›2›1
Strategy
1Your abilities
Keys 1 to 4; 4 is the ultimate:
- 1 · Screwjab Dagger — 10s cooldown: Throw a dagger, dealing spirit damage and applying slow. Every subsequent dagger against the same target stacks in spirit damage and slow.
- 2 · Lethal Venom — 28s cooldown: Inject a target with lethal venom. After a delay the venom triggers, dealing Spirit Damage. The damage is increased by the target's missing health. Lethal Venom will ignore Petrify's damage block.
- 3 · Slither: You have increased Slide Distance, can Slide up hills, and can turn faster while Sliding.
- 4 · Petrifying Bola (ultimate) — 115s cooldown: Throw an explosive bola. On exploding, the bola Slows and Damages all enemies in the area. Direct hits deal Additional Damage and Petrify instead. Petrified units block all damage, but cannot take actions.
2Where to put your first points
Unlock order most players use: Slither (3) → Lethal Venom (2) → Screwjab Dagger (1) → Petrifying Bola (4).
- Upgrade Slither first, then Lethal Venom; put points in the ultimate when you can.
Tips
- Last-hit troopers and shoot the soul orbs they drop: souls are your gold and your level.
- Deny the enemy's orbs when you can: every denied orb is souls they don't get.
- Spend your souls at the shop often: an unspent 3,200 is a tier 3 item you are not using.
- Parry melee attacks when you see them coming: a good parry stuns the attacker.
- Unlock order most players use: Slither (3) → Lethal Venom (2) → Screwjab Dagger (1) → Petrifying Bola (4).
- Upgrade Slither first, then Lethal Venom; put points in the ultimate when you can.
Matchups
Strong against
- Mirage55.2%win rate in the matchup
Vyper wins 55.2% of the 8,675 games measured against Mirage in the last two weeks.
8.7K matches
- Viscous54.2%win rate in the matchup
Vyper wins 54.2% of the 10,668 games measured against Viscous in the last two weeks.
10.7K matches
- Sinclair54.2%win rate in the matchup
Vyper wins 54.2% of the 9,871 games measured against Sinclair in the last two weeks.
9.9K matches
- The Doorman54.1%win rate in the matchup
Vyper wins 54.1% of the 10,424 games measured against The Doorman in the last two weeks.
10.4K matches
- Shiv53.8%win rate in the matchup
Vyper wins 53.8% of the 21,780 games measured against Shiv in the last two weeks.
21.8K matches
Weak against
- Graves41.6%win rate in the matchup
Vyper only wins 41.6% of the 21,433 games measured against Graves in the last two weeks.
21.4K matches
- Victor43.0%win rate in the matchup
Vyper only wins 43.0% of the 18,776 games measured against Victor in the last two weeks.
18.8K matches
- Paige43.2%win rate in the matchup
Vyper only wins 43.2% of the 20,387 games measured against Paige in the last two weeks.
20.4K matches
- Seven44.5%win rate in the matchup
Vyper only wins 44.5% of the 19,239 games measured against Seven in the last two weeks.
19.2K matches
- Kelvin45.0%win rate in the matchup
Vyper only wins 45.0% of the 10,749 games measured against Kelvin in the last two weeks.
10.7K matches
Works well with
- Paige56.6%win rate in the matchup
Vyper and Paige on the same team win 56.6% of 4,322 games measured in the last two weeks.
4.3K matches
- Seven55.3%win rate in the matchup
Vyper and Seven on the same team win 55.3% of 2,470 games measured in the last two weeks.
2.5K matches
- Graves55.0%win rate in the matchup
Vyper and Graves on the same team win 55.0% of 3,965 games measured in the last two weeks.
4K matches
- Victor54.8%win rate in the matchup
Vyper and Victor on the same team win 54.8% of 2,457 games measured in the last two weeks.
2.5K matches
- Kelvin54.4%win rate in the matchup
Vyper and Kelvin on the same team win 54.4% of 2,019 games measured in the last two weeks.
2K matches
Changelog
- Guide created for patch 2026-09-16.
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