Vyper · Assassin
Vyper matchups and synergies
More Vyper guides
This guide is assembled by the site from match data and the game's own information — nobody wrote it by hand. Official and community guides appear alongside it when they exist.
Overview
Vyper is a assassin in Deadlock: slither in and assassinate enemies. Over the last two weeks it is B tier: 49.0% win rate in 107,154 games, picked in 18.9% of matches. Every matchup below comes from real games with at least 200 games behind it.
Strengths
- Wins the lane against Mirage: 56.0% of 2,886 games with both in the same lane.
Weaknesses
- Short-range gun: damage falls off from 15 m, so it has to fight up close.
- Struggles against Graves in lane: only 42.3% of 6,858 games.
Build cheat sheet
Pick the build that fits what you want to do this game.
- Vyper: most played buildBalancedRecommendedThe items Vyper players buy most in each phase of the game over the last two weeks (107,154 games measured), with how many buy them and how they do. Skill points in the most played order (6,328 games, 52.2% win rate).
- Vyper: highest win rate itemsOffensiveSituationalItems with the highest win rate when bought on Vyper, among those bought in a meaningful share of games, placed by when they are bought on average. Win rate on items bought late is inflated by games that were already going well: read it as “what winning Vypers end up buying”.
Builds
Vyper: most played build
When to use it
The items Vyper players buy most in each phase of the game over the last two weeks (107,154 games measured), with how many buy them and how they do. Skill points in the most played order (6,328 games, 52.2% win rate).
Laning phase
Mid game
- 1Burst FireBought by 58.7% of players in this phase · 49.5% win rate
- 2Split ShotBought by 46.4% of players in this phase · 47.4% win rate
- 3Quicksilver ReloadBought by 40.4% of players in this phase · 48.2% win rate
- 4Tesla BulletsBought by 33.5% of players in this phase · 48.7% win rate
- 5Bullet LifestealBought by 27.6% of players in this phase · 47.4% win rate
- 6Extra StaminaBought by 26.3% of players in this phase · 46.4% win rate
Late game
Skill order
Max order:3›2›1
| Ability | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
 1 | · | · | · | · | 1 | · | · | · | · | · | · | · | · | 1 | 1 |
 2 | · | · | 2 | 2 | · | · | · | · | 2 | 2 | · | · | · | · | · |
 3 | 3 | 3 | · | · | · | 3 | · | 3 | · | · | · | · | · | · | · |
 4 | · | · | · | · | · | · | 4 | · | · | · | 4 | 4 | 4 | · | · |
Vyper: highest win rate items
When to use it
Items with the highest win rate when bought on Vyper, among those bought in a meaningful share of games, placed by when they are bought on average. Win rate on items bought late is inflated by games that were already going well: read it as “what winning Vypers end up buying”.
Late game
Skill order
Max order:3›2›1
| Ability | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | · | · | 1 | · | · | · | · | · | · | · | · | · | · | 1 | 1 | 1 |
| 2 | · | · | · | 2 | 2 | · | · | · | 2 | 2 | · | · | · | · | · | · |
| 3 | 3 | 3 | · | · | · | 3 | · | 3 | · | · | · | · | · | · | · | · |
| 4 | · | · | · | · | · | · | 4 | · | · | · | 4 | 4 | 4 | · | · | · |
Abilities
- 1Screwjab Dagger10sThrow a dagger, dealing spirit damage and applying slow. Every subsequent dagger against the same target stacks in spirit damage and slow.
- Damage
- 50
- Move Speed
- -28%
- Damage per Stack
- 25
- Move Speed per Stack
- -12%
- Stack Duration
- 10s
- Charges
- 2
- 2Lethal Venom28sInject a target with lethal venom. After a delay the venom triggers, dealing Spirit Damage. The damage is increased by the target's missing health. Lethal Venom will ignore Petrify's damage block.
- Minimum Venom Damage
- 20
- Max Venom Damage
- 140
- Health for Max Damage
- 30%
- Venom Buildup Duration
- 3s
- 3SlitherYou have increased Slide Distance, can Slide up hills, and can turn faster while Sliding.
- Slide Distance
- +15%
- 4Petrifying BolaUltimate115sThrow an explosive bola. On exploding, the bola Slows and Damages all enemies in the area. Direct hits deal Additional Damage and Petrify instead. Petrified units block all damage, but cannot take actions.
- Damage
- 50
- Petrify Damage
- 180
- Move Speed
- -40%
- Slow Duration
- 1.5s
Most played skill order
The most played order in the last 6328 professional matches with this hero. Highlighted levels are the points spent on talents.
Max order:3›2›1
| Ability | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | · | · | · | · | 1 | · | · | · | · | · | · | · | · | 1 | 1 |
| 2 | · | · | 2 | 2 | · | · | · | · | 2 | 2 | · | · | · | · | · |
| 3 | 3 | 3 | · | · | · | 3 | · | 3 | · | · | · | · | · | · | · |
| 4 | · | · | · | · | · | · | 4 | · | · | · | 4 | 4 | 4 | · | · |
Strategy
1Strong against
Whole game, any lane:
- Mirage: 55.3% over 8,394 games
- Viscous: 54.1% over 10,402 games
- Sinclair: 54.1% over 9,544 games
- The Doorman: 54.0% over 10,042 games
- Shiv: 53.5% over 21,256 games
2Weak against
Whole game, any lane:
- Graves: 41.6% over 20,543 games
- Victor: 42.9% over 17,990 games
- Paige: 43.1% over 19,612 games
- Seven: 44.5% over 18,422 games
- Mo & Krill: 45.2% over 14,911 games
3Best teammates
Win rate with both on the same team:
4In the same lane
Only games where both started in the same lane:
- Mirage: 56.0% over 2,886 games
- Sinclair: 55.0% over 3,268 games
- Viscous: 53.7% over 3,744 games
- Shiv: 53.6% over 7,532 games
- Paradox: 53.1% over 4,375 games
- Graves: 42.3% over 6,858 games
- Paige: 42.9% over 7,718 games
- Victor: 43.7% over 6,499 games
- Seven: 44.7% over 6,590 games
- Mo & Krill: 45.0% over 4,771 games
Matchups
Strong against
- Mirage55.3%win rate in the matchup
Vyper wins 55.3% of the 8,394 games measured against Mirage in the last two weeks.
8.4K matches
- Viscous54.1%win rate in the matchup
Vyper wins 54.1% of the 10,402 games measured against Viscous in the last two weeks.
10.4K matches
- Sinclair54.1%win rate in the matchup
Vyper wins 54.1% of the 9,544 games measured against Sinclair in the last two weeks.
9.5K matches
- The Doorman54.0%win rate in the matchup
Vyper wins 54.0% of the 10,042 games measured against The Doorman in the last two weeks.
10K matches
- Shiv53.5%win rate in the matchup
Vyper wins 53.5% of the 21,256 games measured against Shiv in the last two weeks.
21.3K matches
Weak against
- Graves41.6%win rate in the matchup
Vyper only wins 41.6% of the 20,543 games measured against Graves in the last two weeks.
20.5K matches
- Victor42.9%win rate in the matchup
Vyper only wins 42.9% of the 17,990 games measured against Victor in the last two weeks.
18K matches
- Paige43.1%win rate in the matchup
Vyper only wins 43.1% of the 19,612 games measured against Paige in the last two weeks.
19.6K matches
- Seven44.5%win rate in the matchup
Vyper only wins 44.5% of the 18,422 games measured against Seven in the last two weeks.
18.4K matches
- Mo & Krill45.2%win rate in the matchup
Vyper only wins 45.2% of the 14,911 games measured against Mo & Krill in the last two weeks.
14.9K matches
Works well with
- Paige56.4%win rate in the matchup
Vyper and Paige on the same team win 56.4% of 4,211 games measured in the last two weeks.
4.2K matches
- Graves55.4%win rate in the matchup
Vyper and Graves on the same team win 55.4% of 3,784 games measured in the last two weeks.
3.8K matches
- Seven55.0%win rate in the matchup
Vyper and Seven on the same team win 55.0% of 2,372 games measured in the last two weeks.
2.4K matches
- Victor54.8%win rate in the matchup
Vyper and Victor on the same team win 54.8% of 2,330 games measured in the last two weeks.
2.3K matches
- Kelvin54.4%win rate in the matchup
Vyper and Kelvin on the same team win 54.4% of 1,933 games measured in the last two weeks.
1.9K matches
Changelog
- Guide created for patch 2026-09-16.
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